What Has Methylation Done For You Lately?
Epigenetics is the study of heritable changes in the phenotype of a cell or an organism that are not encoded by the genome (hence epi which means ‘above’ in Greek, and genetikos which means ‘origin’)....
View ArticleA Crash Course in Epigenetics Part 1: An intro to epigenetics
These days, epigenetics is a fast moving field. I don’t remember having learnt about it during my biomedical studies, some 10 years ago. Nowadays, there seems to be no way around it when studying...
View ArticleA Crash Course in Epigenetics Part 2: The toolbox of the epigeneticist
In the past decade, important advances have been made in the field of epigenetics. Obviously, unraveling epigenetic mechanisms has been greatly facilitated by technological developments. I’ll try to...
View ArticleA Crash Course in Epigenetics Part 3: Regulated regulation
Epigenetics is the most rapidly expanding field in biology. In the second article in this series, I discussed which experimental techniques have been crucial in gaining insight into epigenetic...
View ArticleA Crash Course in Epigenetics Part 4: Disease mechanisms and therapeutic targets
After having discussed what epigenetic mechanisms are and how we’ve learnt about what they do, it is now time to look into how epigenetics affect our lives if things do not go the way they are supposed...
View ArticleGetting the most out of your human DNA methylation studies
The field of epigenetics is exploding and given the strong links between epigenetic state and disease, the need to study markers like DNA methylation in humans is very relevant. This article outlines...
View ArticleConrad Waddington and his epigenetic landscape
I was first introduced to Conrad Waddington’s epigenetic landscape when reading ‘The epigenetic revolution’, a fantastic introduction to epigenetics, and in my opinion, a must read for anyone who is...
View ArticleEZ DNA Methylation Kits: The most trusted, cited and efficient kits on the...
Accurate and reliable methods to detect DNA methylation patterns are vital for researchers interested in the study of epigenetics. Understanding methylation profiles can be used for disease...
View ArticleHow Bisulfite Pyrosequencing Works
Bisulfite pyrosequencing is becoming a routine technique in molecular biology labs as a method to precisely measure DNA methylation levels right down to the single base. The technique allows for...
View ArticleLiquid Biopsy Sample Handling
In this webinar you will learn: How to sensitively, specifically and rapidly analyze circulating free nucleic acids (cfDNA), circulating tumor cells (CTCs) or exosomes from a blood sample using liquid...
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